Description

(R)-1,2-Dihydroacenaphthylen-1-Amine CAS NO 228246-73-9 is a chiral amine derivative of acenaphthene, serving as a valuable non-natural amino acid building block and chiral ligand precursor. This compound is critical for the synthesis of complex molecules where stereochemical control is paramount. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the asymmetric synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Development: Used in creating enantiomerically pure herbicides, fungicides, and plant growth regulators with enhanced efficacy and environmental profiles.
• Catalyst & Ligand Synthesis: Serves as a precursor for chiral ligands in transition metal catalysis, enabling asymmetric hydrogenation and C-C bond-forming reactions.
• Material Science Research: Employed in the development of chiral organic semiconductors, liquid crystals, and polymers with specific optical properties.
• Academic & Process Chemistry: A versatile building block for methodological studies in organic synthesis and scale-up process development.

Basic Information

Product Name	(R)-1,2-Dihydroacenaphthylen-1-Amine
CAS No.	228246-73-9
Molecular Formula	C₁₂H₁₁N
Molecular Weight	169.22 g/mol
Synonyms	(1R)-1,2-Dihydroacenaphthylen-1-amine; (R)-1-Amino-1,2-dihydroacenaphthylene; (R)-1,2-Dihydro-1-acenaphthylenamine; (R)-1-Acenaphthenylamine; (R)-Acenaphthen-1-ylamine; (1R)-1-Aminoacenaphthene; (R)-1,2-Dihydroacenaphthylene-1-amine; (R)-1,2-Dihydro-1-acenaphthylamine
EINECS	Contact for details

Quality Control

Our (R)-1,2-Dihydroacenaphthylen-1-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.