Description

.Beta.-D-Gulopyranose, 1,6-Anhydro-3-Bis(Phenylmethyl)Amino-3-Deoxy-2-o-(1,5-Dihydro-3-Oxido-2,4,3-Benzodioxaphosphepin-3-Yl)-4-o-(Tetrahydro-2H-Pyran-2-Yl)- is a sophisticated, multi-functional carbohydrate derivative featuring a unique benzodioxaphosphepin moiety. This compound is engineered as a key chiral intermediate for advanced organic synthesis, particularly in the development of novel pharmaceuticals and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of complex nucleoside analogs, enzyme inhibitors, and other high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Chiral Ligand/ Catalyst Precursor: Used in asymmetric synthesis due to its complex stereochemistry and phosphorus-containing functional group.
• Glycobiology Research: Serves as a modified sugar substrate for studying enzyme mechanisms and carbohydrate-protein interactions.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and the development of glycosidase inhibitors.
• Chemical Biology Probe: Utilized to label or modulate biological systems, leveraging its unique reactive handles.
• Process Chemistry Development: Acts as a high-value intermediate in the scale-up and optimization of synthetic routes for complex active pharmaceutical ingredients (APIs).

Basic Information

Product Name	.Beta.-D-Gulopyranose, 1,6-Anhydro-3-Bis(Phenylmethyl)Amino-3-Deoxy-2-o-(1,5-Dihydro-3-Oxido-2,4,3-Benzodioxaphosphepin-3-Yl)-4-o-(Tetrahydro-2H-Pyran-2-Yl)-
CAS No.	228115-46-6
Molecular Formula	C34H39NO8P
Molecular Weight	620.65 g/mol
Synonyms	1,6-Anhydro-3-bis(phenylmethyl)amino-3-deoxy-2-O-(1,5-dihydro-3-oxido-2,4,3-benzodioxaphosphepin-3-yl)-4-O-(tetrahydro-2H-pyran-2-yl)-β-D-glucopyranose; 3-N,N-Dibenzylamino-3-deoxy-1,6-anhydro-2-O-(3-oxido-2,4,3-benzodioxaphosphepin-3-yl)-4-O-tetrahydropyran-2-yl-β-D-glucopyranose; 3-Dibenzylamino-3-deoxy-1,6-anhydro-2-O-(3H-2,4,3-benzodioxaphosphepin-3-yl)-4-O-(tetrahydropyran-2-yl)-β-D-glucopyranose 3-oxide; Benzodioxaphosphepin-modified glucopyranose derivative; THP-protected anhydro sugar phosphonate.
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our advanced intermediates. Each batch of .Beta.-D-Gulopyranose derivative is analyzed using advanced chromatographic and spectroscopic techniques to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), chiral purity, and impurity profile is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the primary container for extended periods to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.