Description

5-Chloro-2-(Phenylthio)-Indole is a high-purity, synthetically valuable indole derivative characterized by its chloro and phenylthio substituents. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis, enabling the construction of complex molecular architectures. It is primarily required by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, to create complex indole-based compounds.
• Material Science Precursor: Investigated for the synthesis of organic semiconductors, dyes, and photochromic materials due to its electron-rich indole structure.
• Biochemical Tool Compound: Utilized in academic and industrial research to study enzyme inhibition and receptor binding activities.

Basic Information

Product Name	5-Chloro-2-(Phenylthio)-Indole
CAS No.	227803-36-3
Molecular Formula	C14H10ClNS
Molecular Weight	259.75 g/mol
Synonyms	5-Chloro-2-(phenylthio)-1H-indole; 2-(Phenylthio)-5-chloroindole; 5-Chloro-2-(phenylsulfanyl)-1H-indole; 5-Chloro-2-(phenylmercapto)indole; 1H-Indole, 5-chloro-2-(phenylthio)-; 227803-36-3; 5-Chloro-2-phenylsulfanylindole
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-(Phenylthio)-Indole is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our production adheres to cGMP guidelines where applicable, ensuring consistency and reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to air and moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.