Description

5-Chloro-3-(Phenylthio)-Indole is a high-purity, synthetically valuable indole derivative, distinguished by its chloro and phenylthio substituents. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the development of novel bioactive molecules. It is primarily required by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Building block for developing novel pesticides and herbicides with specific modes of action.
• Material Science: Monomer or precursor for functional polymers and organic electronic materials due to the indole core's electron-rich properties.
• Chemical Biology: Probe or linker molecule in biochemical assay development and proteomics research.
• Academic & Contract Research: Essential reagent for methodological studies in organic chemistry, particularly in C-H functionalization and cross-coupling reactions.
• Dye & Pigment Intermediate: Used in the research and development of specialized indole-based colorants.

Basic Information

Product Name	5-Chloro-3-(Phenylthio)-Indole
CAS No.	227803-35-2
Molecular Formula	C14H10ClNS
Molecular Weight	259.75 g/mol
Synonyms	5-Chloro-3-(phenylthio)-1H-indole; 3-(Phenylthio)-5-chloroindole; 5-Chloro-3-phenylsulfanyl-1H-indole; 1H-Indole, 5-chloro-3-(phenylthio)-; 5-Chloro-3-(phenylmercapto)indole; 5-Chloro-3-(benzenethiolato)indole; 5-Chloro-3-(phenylsulfanyl)indole; 5-Chloro-3-(thiophenoxy)indole
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-3-(Phenylthio)-Indole is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical intermediate grade meets stringent in-house specifications. A detailed Certificate of Analysis (COA) documenting purity (typically by HPLC), identity (IR, NMR), and impurity profile is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.