Description

2-Bromo-5-Fluoro-Benzo[B]Thiophene is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique halogenated structure, which enables precise molecular modifications in complex chemical pathways. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive thiophene core.
• Material Science: Serves as a building block for organic semiconductors, liquid crystals, and advanced polymers.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) to introduce functionalized benzo[b]thiophene motifs into larger molecular architectures.
• Academic & Industrial R&D: A versatile reagent for methodological studies and the discovery of new chemical entities in laboratory settings.

Basic Information

Product Name	2-Bromo-5-Fluoro-Benzo[B]Thiophene
CAS No.	227802-37-1
Molecular Formula	C8H4BrFS
Molecular Weight	231.09 g/mol
Synonyms	2-Bromo-5-fluorobenzo[b]thiophene; 5-Fluoro-2-bromobenzo[b]thiophene; 2-Bromo-5-fluorobenzo[b]thiophene; 2-Bromo-5-fluoro-1-benzothiophene; 227802-37-1; Benzo[b]thiophene, 2-bromo-5-fluoro-; 5-Fluoro-2-bromobenzo[b]thiophene
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Fluoro-Benzo[B]Thiophene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.