Description

Methyl 3-Amino-3-(Thiophen-2-Yl)Propanoate Hydrochloride is a high-purity, pharmaceutically relevant intermediate characterized by its unique thiophene-based structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and complex organic molecules, offering a versatile chiral building block. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging the thiophene moiety for enhanced biological activity.
• Organic Synthesis Building Block: Serves as a versatile precursor for constructing complex heterocyclic compounds and fine chemicals in academic and industrial R&D.
• Peptidomimetics Research: Employed in the design and synthesis of peptide analogs and mimetics for biochemical studies and drug discovery programs.
• Material Science Precursor: Potential use in the synthesis of functionalized monomers for advanced polymers and electronic materials.

Basic Information

Product Name	Methyl 3-Amino-3-(Thiophen-2-Yl)Propanoate Hydrochloride
CAS No.	227597-67-3
Molecular Formula	C8H12ClNO2S
Molecular Weight	221.70 g/mol
Synonyms	3-Amino-3-(2-thienyl)propanoic acid methyl ester hydrochloride; Methyl 3-amino-3-(2-thienyl)propionate hydrochloride; 3-(Thiophen-2-yl)-3-aminopropionic acid methyl ester HCl; 2-Thiophenepropanoic acid, 3-amino-, methyl ester, hydrochloride; Methyl β-amino-β-(2-thienyl)propionate hydrochloride; (R/S)-Methyl 3-amino-3-(thiophen-2-yl)propanoate hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-3-(Thiophen-2-Yl)Propanoate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.