Description

tert-Butyl (5-Nitro-1H-Indol-1-Yl)Acetate is a specialized indole derivative, a high-value intermediate in advanced organic synthesis. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for creating novel pharmacologically active molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Employed in the development of new active ingredients for crop protection products, leveraging its heterocyclic core.
• Fine Chemical Production: Serves as a building block for synthesizing complex, high-value specialty chemicals and advanced materials.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for methodological development and exploratory synthesis.

Basic Information

Product Name	tert-Butyl (5-Nitro-1H-Indol-1-Yl)Acetate
CAS No.	227302-34-3
Molecular Formula	C₁₄H₁₆N₂O₄
Molecular Weight	276.29 g/mol
Synonyms	1H-Indole-1-acetic acid, 5-nitro-, 1,1-dimethylethyl ester; tert-Butyl 2-(5-nitro-1H-indol-1-yl)acetate; 2-(5-Nitro-1H-indol-1-yl)acetic acid tert-butyl ester; (5-Nitro-1H-indol-1-yl)acetic acid tert-butyl ester; 1-(tert-Butoxycarbonylmethyl)-5-nitroindole; 5-Nitroindole-1-acetic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl (5-Nitro-1H-Indol-1-Yl)Acetate is produced and tested under strict quality management protocols to ensure consistency and reliability for critical synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.