Description

5-Aminomethyl-2-Cyanothiophene is a versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its bifunctional molecular architecture, featuring both a reactive aminomethyl group and a cyano substituent on a thiophene core, enabling diverse chemical transformations. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds and potential drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used as a building block for developing novel herbicides, fungicides, and insecticides with thiophene-based scaffolds.
• Material Science Research: Serves as a monomer or precursor for conductive polymers, organic semiconductors, and advanced functional materials.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where the thiophene ring contributes to color and stability properties.
• Ligand and Catalyst Development: Utilized to create novel chelating ligands for metal catalysis and coordination chemistry applications.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring tailored molecular structures.

Basic Information

Product Name	5-Aminomethyl-2-Cyanothiophene
CAS No.	227279-10-9
Molecular Formula	C6H6N2S
Molecular Weight	138.19 g/mol
Synonyms	2-Cyano-5-(aminomethyl)thiophene; 5-(Aminomethyl)thiophene-2-carbonitrile; Thiophene-2-carbonitrile, 5-(aminomethyl)-; 2-Thiophenecarbonitrile, 5-(aminomethyl)-; 5-Cyanomethyl-2-aminothiophene (tautomeric form); 2-Cyano-5-thiophenemethylamine; 5-Aminomethylthiophene-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Aminomethyl-2-Cyanothiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets exacting standards for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.