Description

6-Bromo-1,2,3,4-Tetrahydroisoquinoline is a versatile brominated heterocyclic building block of significant importance in advanced organic synthesis. Its core structure serves as a key intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in drug discovery, agrochemicals, and material science.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.
• Medicinal Chemistry Scaffold: Used to build and diversify compound libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Employed in the synthesis of organic ligands, catalysts, and advanced functional materials.
• Chemical Biology Probes: Utilized to create labeled compounds and probes for studying biological mechanisms and pathways.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic chemistry research.

Basic Information

Product Name	6-Bromo-1,2,3,4-Tetrahydroisoquinoline
CAS No.	226942-29-6
Molecular Formula	C9H10BrN
Molecular Weight	212.09 g/mol
Synonyms	6-Bromo-1,2,3,4-tetrahydroisoquinoline; 6-Bromotetrahydroisoquinoline; 1,2,3,4-Tetrahydro-6-bromoisoquinoline; 6-Bromo-THIQ; 226942-29-6; 6-Bromo-1,2,3,4-tetrahydro-isoquinoline
EINECS	Contact for details

Quality Control

Our 6-Bromo-1,2,3,4-Tetrahydroisoquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We support custom synthesis to meet specific purity requirements, including research-grade and GMP-grade standards for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.