Description

5-Nitro-1-Indoleacetic Acid is a specialized nitro-substituted indole derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in its dual functional groups, which make it a versatile building block for constructing complex heterocyclic molecules and fine-tuning molecular properties. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel indole-based drug candidates, particularly for targeting specific biological pathways.
• Agrochemical Research: Used in developing new plant growth regulators or herbicides due to its structural similarity to auxin-like compounds.
• Organic Synthesis Building Block: Serves as a versatile starting material for constructing complex heterocyclic frameworks in medicinal and process chemistry.
• Biochemical Research: Potential use as a probe or inhibitor in enzymatic studies involving indole metabolism.
• Material Science: Intermediate for synthesizing specialized dyes, pigments, or organic electronic materials with nitro-functionalized indole cores.
• Contract Research & Manufacturing (CRAM): Supplied to organizations requiring high-purity, custom synthetic intermediates for client projects.

Basic Information

Product Name	5-Nitro-1-Indoleacetic Acid
CAS No.	226901-50-4
Molecular Formula	C10H8N2O4
Molecular Weight	220.18 g/mol
Synonyms	1H-Indole-1-acetic acid, 5-nitro-; 5-Nitroindole-1-acetic acid; (5-Nitro-1H-indol-1-yl)acetic acid; 2-(5-Nitro-1H-indol-1-yl)acetic acid; 5-Nitro-1H-indole-1-acetic acid; 5-Nitroindol-1-ylacetic acid; 226901-50-4; 5-Nitro-1-indolylacetic acid
EINECS	Contact for details

Quality Control

Our 5-Nitro-1-Indoleacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.