Description

2,3,5-Trifluorobenzyl Bromide is a high-value fluorinated benzyl bromide derivative, a crucial building block in advanced organic synthesis. Its importance lies in its ability to introduce the 2,3,5-trifluorobenzyl moiety, a key structural feature that can significantly alter the physical, chemical, and biological properties of target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients with enhanced efficacy and selectivity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in CNS and oncology drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides where the trifluoromethyl/fluorine motif improves bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and material science.
• Liquid Crystal and OLED Materials: Incorporated into the synthesis of fluorinated organic electronic materials to modify charge transport and emission properties.
• Fluorinated Polymer Modifiers: Acts as a monomer or grafting agent to introduce fluorine into polymer backbones, enhancing chemical resistance and thermal stability.
• Positron Emission Tomography (PET) Tracer Precursor: Utilized in radiochemistry for labeling compounds with fluorine-18 for diagnostic imaging.

Basic Information

Product Name	2,3,5-Trifluorobenzyl Bromide
CAS No.	226717-83-5
Molecular Formula	C7H4BrF3
Molecular Weight	225.01 g/mol
Synonyms	(2,3,5-Trifluorophenyl)methyl Bromide; 1-(Bromomethyl)-2,3,5-trifluorobenzene; α-Bromo-2,3,5-trifluorotoluene; 2,3,5-Trifluoro-α-bromotoluene; 2,3,5-Trifluorobenzylbromide; Bromo(2,3,5-trifluorophenyl)methane
EINECS	Contact for details

Quality Control

Our 2,3,5-Trifluorobenzyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and GC-MS and NMR for identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents. Due to its sensitivity to light and moisture, containers should be kept sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.