Description

tert-Butyl 5-Methylindoline-1-Carboxylate is a high-purity, protected indoline derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). Pharmaceutical researchers and fine chemical manufacturers need it for its utility in medicinal chemistry, where it acts as a key building block for potential drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research for central nervous system (CNS) and oncology targets.
• Organic Synthesis Reagent: Used in multi-step synthesis to introduce the protected indoline moiety, facilitating further functionalization and ring formation.
• Agrochemical Research: Serves as a precursor in the development of new crop protection agents and pesticides with complex heterocyclic structures.
• Material Science Chemistry: Employed in the research and synthesis of organic electronic materials and advanced polymers.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploring new chemical reactions in university and industrial research settings.

Basic Information

Product Name	tert-Butyl 5-Methylindoline-1-Carboxylate
CAS No.	226710-78-7
Molecular Formula	C15H21NO2
Molecular Weight	247.33 g/mol
Synonyms	1-Boc-5-Methylindoline; 5-Methylindoline-1-carboxylic acid tert-butyl ester; tert-Butyl 5-methyl-2,3-dihydro-1H-indole-1-carboxylate; 1-N-Boc-5-methylindoline; Boc-5-methylindoline; 226710-78-7; 5-Methyl-1H-indole-1-carboxylic acid, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-Methylindoline-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.