Description

(1R,5S,7S,8S)-7-Methoxy-8-(Phenylmethoxy)-3,6-Dioxabicyclo[3.2.1]Octane-5-Methanol is a high-purity, advanced pharmaceutical intermediate characterized by its complex bicyclic acetal structure. This compound is of significant value in organic synthesis, particularly for the construction of complex carbohydrate mimetics and nucleoside analogs. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel antiviral and anticancer therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of nucleoside and nucleotide analogs for antiviral and anticancer drug discovery.
• Carbohydrate Chemistry: Used in the preparation of complex sugar derivatives and glycomimetics for biochemical research and drug development.
• Asymmetric Synthesis: Serves as a versatile chiral synthon for constructing complex molecular architectures with defined stereochemistry.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Academic Research: A valuable reagent for studying reaction mechanisms and developing new synthetic methodologies in organic chemistry.

Basic Information

Product Name	(1R,5S,7S,8S)-7-Methoxy-8-(Phenylmethoxy)-3,6-Dioxabicyclo[3.2.1]Octane-5-Methanol
CAS No.	226214-50-2
Molecular Formula	C₁₆H₂₂O₆
Molecular Weight	310.34 g/mol
Synonyms	7-Methoxy-8-(benzyloxy)-3,6-dioxabicyclo[3.2.1]octane-5-methanol, (1R,5S,7S,8S)-form; (1R,5S,7S,8S)-7-Methoxy-8-(benzyloxy)-3,6-dioxabicyclo[3.2.1]octane-5-methanol; Bicyclo[3.2.1]octane-5-methanol, 7-methoxy-8-(phenylmethoxy)-3,6-dioxa-, (1R,5S,7S,8S)-; CAS 226214-50-2; Advanced Nucleoside Intermediate; Chiral Bicyclic Acetal Synthon.
EINECS	Contact for details

Quality Control

Our (1R,5S,7S,8S)-7-Methoxy-8-(Phenylmethoxy)-3,6-Dioxabicyclo[3.2.1]Octane-5-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and specific test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.