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(R)-1-(2,6-Dichloro-Phenyl)-Ethanol CAS NO 225920-08-1


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CAS No.:225920-08-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(R)-1-(2,6-Dichloro-Phenyl)-Ethanol is a high-purity chiral intermediate of significant importance in modern asymmetric synthesis. This compound matters as a key building block for the development of enantiomerically pure active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel, high-value compounds.

Application

  • Pharmaceutical Intermediate: A crucial chiral synthon for the research and production of enantiomerically pure drugs, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
  • Agrochemical Synthesis: Used in the development of advanced, stereospecific pesticides and herbicides where the specific (R)-enantiomer activity is required.
  • Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis, such as hydrogenation or cross-coupling reactions.
  • Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require high optical purity.
  • Academic & Industrial R&D: A valuable reference standard and building block for method development and discovery chemistry in synthetic organic laboratories.

Basic Information

Product Name (R)-1-(2,6-Dichloro-Phenyl)-Ethanol
CAS No. 225920-08-1
Molecular Formula C8H8Cl2O
Molecular Weight 191.05 g/mol
Synonyms (R)-2,6-Dichloro-α-methylbenzyl alcohol; (R)-1-(2,6-Dichlorophenyl)ethanol; (R)-α-Methyl-2,6-dichlorobenzyl alcohol; (R)-2,6-Dichloro-α-phenylethanol; (R)-2,6-Dichlorophenyl methyl carbinol; (R)-1-(2,6-Dichlorophenyl)ethyl alcohol; (R)-Enantiomer of 1-(2,6-Dichlorophenyl)ethanol
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Quality Control

Our (R)-1-(2,6-Dichloro-Phenyl)-Ethanol is produced under strict quality management systems to ensure batch-to-batch consistency and high optical purity. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing chiral purity, chemical purity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Chiral Purity (Chiral HPLC) ≥ 99.0% ee (R)
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Related Substances (HPLC) Total impurities ≤ 1.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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