Description

2-(5-(7-Chlorothieno[3,2-B]Pyridin-2-Yl)-1-Methyl-1H-Imidazol-2-Yl)Propan-2-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of critical importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, especially within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a key scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Oncology Drug Development: Used in the research and development of targeted cancer therapies due to its specific heterocyclic framework.
• CNS-Active Compound Synthesis: Employed in creating potential therapeutics for neurological and psychiatric disorders.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	2-(5-(7-Chlorothieno[3,2-B]Pyridin-2-Yl)-1-Methyl-1H-Imidazol-2-Yl)Propan-2-Ol
CAS No.	225385-10-4
Molecular Formula	C16H14ClN3OS
Molecular Weight	331.82 g/mol
Synonyms	2-[5-(7-Chlorothieno[3,2-b]pyridin-2-yl)-1-methyl-1H-imidazol-2-yl]propan-2-ol; 2-(5-(7-Chlorothieno[3,2-b]pyridin-2-yl)-1-methyl-1H-imidazol-2-yl)-2-propanol; 7-Chloro-2-[2-(2-hydroxy-2-propanyl)-1-methyl-1H-imidazol-5-yl]thieno[3,2-b]pyridine; 225385-10-4; Advanced Pharmaceutical Intermediate 225385-10-4; Thienopyridine-imidazole derivative
EINECS	Contact for details

Quality Control

Our 2-(5-(7-Chlorothieno[3,2-B]Pyridin-2-Yl)-1-Methyl-1H-Imidazol-2-Yl)Propan-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.