Description

(S)-1-(Thiophen-2-Yl)But-3-En-1-Amine is a chiral amine building block of significant importance in modern synthetic chemistry. This compound matters as a key intermediate for the synthesis of complex, biologically active molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, where its chiral center can influence biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands used in asymmetric catalysis to create enantiomerically pure compounds.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Advanced Material Research: Acts as a monomer or functionalization agent in the development of specialty polymers and functional organic materials.
• Custom Synthesis and Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-purity, enantiomerically defined intermediates.

Basic Information

Product Name	(S)-1-(Thiophen-2-Yl)But-3-En-1-Amine
CAS No.	224453-38-7
Molecular Formula	C8H11NS
Molecular Weight	153.24 g/mol
Synonyms	(S)-1-(Thiophen-2-yl)but-3-en-1-amine; (S)-1-(2-Thienyl)-3-buten-1-amine; (S)-1-(Thiophen-2-yl)but-3-en-1-amine; (2S)-1-(Thiophen-2-yl)but-3-en-1-amine; (S)-1-(2-Thienyl)-3-butenylamine; (S)-1-(Thien-2-yl)-3-buten-1-amine; (S)-1-(2-Thienyl)-3-buten-1-amine; (S)-1-(Thiophen-2-yl)but-3-en-1-amine hydrochloride (if applicable).
EINECS	Contact for details

Quality Control

Our (S)-1-(Thiophen-2-Yl)But-3-En-1-Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity determination by HPLC, to ensure compliance with exacting standards for research and development use. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Enantiomeric Excess)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.