Description

1-Azabicyclo[2.2.1]Heptane-3-Methanol,(1S,3R,4S)-(9Ci) is a high-purity, stereochemically defined bicyclic amine derivative that serves as a critical chiral building block in advanced organic synthesis. Its rigid, three-dimensional structure and defined stereochemistry make it invaluable for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by research institutions and pharmaceutical companies for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize sophisticated ligands for transition metal catalysis, enabling highly enantioselective transformations.
• Agrochemical Synthesis: Employed in the creation of novel, stereospecific pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science Research: Acts as a monomer or functional additive in the development of advanced polymers and specialty materials with unique properties.
• Academic & Process Chemistry: Utilized in methodological studies and scale-up process development for complex organic molecules.

Basic Information

Product Name	1-Azabicyclo[2.2.1]Heptane-3-Methanol,(1S,3R,4S)-(9Ci)
CAS No.	224297-26-1
Molecular Formula	C7H13NO
Molecular Weight	127.18 g/mol
Synonyms	(1S,3R,4S)-1-Azabicyclo[2.2.1]heptane-3-methanol; (1S,3R,4S)-3-(Hydroxymethyl)-1-azabicyclo[2.2.1]heptane; endo-3-(Hydroxymethyl)-1-azabicyclo[2.2.1]heptane; 1-Azabicyclo[2.2.1]heptane-3-methanol, (1S,3R,4S)-; Bicyclic amino alcohol derivative
EINECS	Contact for details

Quality Control

Every batch of 1-Azabicyclo[2.2.1]Heptane-3-Methanol,(1S,3R,4S)-(9Ci) is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and stereochemical integrity, with typical purity levels exceeding 97% (by HPLC). A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as assay, enantiomeric excess, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.