Description

7-Bromo-4-Chloroisoquinolin-1(2H)-One CAS NO 223671-87-2 is a high-purity halogenated isoquinolinone derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its halogenated structure for bioactivity.
• Material Science: Potential precursor for organic electronic materials or specialty polymers due to its fused aromatic system.
• Chemical Synthesis: Serves as a versatile substrate for further functionalization via cross-coupling reactions, nucleophilic substitutions, or metal-catalyzed transformations.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Product Name	7-Bromo-4-Chloroisoquinolin-1(2H)-One
CAS No.	223671-87-2
Molecular Formula	C9H5BrClNO
Molecular Weight	258.50 g/mol
Synonyms	7-Bromo-4-chloro-1,2-dihydroisoquinolin-1-one; 7-Bromo-4-chloro-2H-isoquinolin-1-one; 4-Chloro-7-bromoisoquinolin-1(2H)-one; 1(2H)-Isoquinolinone, 7-bromo-4-chloro-; 223671-87-2; 7-Bromo-4-chloro-1-isoquinolinol; 4-Chloro-7-bromo-1,2-dihydroisoquinolin-1-one
EINECS	Contact for details

Quality Control

Our 7-Bromo-4-Chloroisoquinolin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.