Description

3-(1,4-Dichloro-1,2-Dihydroisoquinolin-7-Yl)Benzonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique dihydroisoquinoline core structure. This compound is of significant value for research and development in medicinal chemistry, particularly for creating novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules. The compound is supplied with full analytical documentation to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new chemical entities.
• Organic Synthesis Reference Standard: Serves as a pure reference material for analytical method development and validation in QC laboratories.
• Biochemical Tool Compound: May be utilized in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Fine Chemical Synthesis: Employed in multi-step synthetic routes to create more complex heterocyclic compounds for various applications.

Basic Information

Item	Details
Product Name	3-(1,4-Dichloro-1,2-Dihydroisoquinolin-7-Yl)Benzonitrile
CAS No.	223671-44-1
Molecular Formula	C16H10Cl2N2
Molecular Weight	301.17 g/mol
Synonyms	7-(3-Cyanophenyl)-1,4-dichloro-1,2-dihydroisoquinoline; 3-(1,4-Dichloro-3,4-dihydro-2H-isoquinolin-7-yl)benzonitrile; 1,4-Dichloro-7-(3-cyanophenyl)-1,2-dihydroisoquinoline; 223671-44-1; 3-(1,4-Dichloro-1,2-dihydroisoquinolin-7-yl)benzonitrile; Benzonitrile, 3-(1,4-dichloro-1,2-dihydro-7-isoquinolinyl)-
EINECS	Contact for details

Quality Control

Every batch of 3-(1,4-Dichloro-1,2-Dihydroisoquinolin-7-Yl)Benzonitrile is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles ensures traceability and reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.