Description

5-Bromo-2-Isoquinolin-2-One is a versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, including kinase inhibitors and other biologically relevant small molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Serves as a building block for creating specialized organic ligands, dyes, and functional polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes for studying biological processes and protein interactions.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting exploratory chemistry and method development.
• Custom Synthesis: A starting material for the bespoke manufacturing of complex, high-value specialty chemicals.

Basic Information

Product Name	5-Bromo-2-Isoquinolin-2-One
CAS No.	223671-17-8
Molecular Formula	C9H6BrNO
Molecular Weight	224.06 g/mol
Synonyms	5-Bromoisoquinolin-2(1H)-one; 2(1H)-Isoquinolinone, 5-bromo-; 5-Bromo-1,2-dihydroisoquinolin-2-one; 5-Bromo-2-hydroxyisoquinoline; 5-Bromoisocarbostyril; 5-Bromo-2-isoquinolinol; 5-Bromo-2-isoquinolinone
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Isoquinolin-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.