Description

7-Bromo-1,4-dichloroisoquinoline is a high-purity halogenated isoquinoline derivative, a crucial advanced intermediate in modern organic synthesis. Its value lies in its unique polyhalogenated structure, which provides multiple reactive sites for selective functionalization, enabling the construction of complex heterocyclic scaffolds. This compound is primarily sought by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the isoquinoline core for bioactivity.
• Material Science Precursor: Serves as a monomer or precursor for creating specialized organic electronic materials and ligands for metal-organic frameworks (MOFs).
• Chemical Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution due to its reactive bromo and chloro substituents.
• Academic & R&D: Essential for methodological studies in organic chemistry and for exploring new synthetic pathways in university and corporate laboratories.

Basic Information

Product Name	7-Bromo-1,4-Dichloroisoquinoline
CAS No.	223671-13-4
Molecular Formula	C9H4BrCl2N
Molecular Weight	276.95 g/mol
Synonyms	7-Bromo-1,4-dichloro-isoquinoline; Isoquinoline, 7-bromo-1,4-dichloro-; 1,4-Dichloro-7-bromoisoquinoline; 7-Bromo-1,4-dichloroisoquinoline; 223671-13-4; 7-Br-1,4-Cl2-Isoquinoline; 7-Bromo-1,4-dichloro-2-azanaphthalene
EINECS	Contact for details

Quality Control

Every batch of 7-Bromo-1,4-dichloroisoquinoline is manufactured and tested under strict quality management protocols. We ensure high chemical purity and consistency suitable for demanding research and scale-up applications. Comprehensive analytical testing, including HPLC, NMR, and GC-MS, is performed to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.