Description

1-(4-Chloro-7-(Phenylthio)Isoquinolin-1-Yl)Guanidine Hydrochloride is a high-purity, specialized organic compound with the CAS number 223671-08-7. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in modern synthetic chemistry. It is primarily utilized by research institutions and industrial manufacturers engaged in the development of novel therapeutic agents and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and CNS research.
• Chemical Synthesis Building Block: Used for constructing complex heterocyclic frameworks in medicinal chemistry and material science.
• Biochemical Research: Employed in the study of enzyme inhibition and receptor-ligand interactions as a specialized probe or inhibitor scaffold.
• Agrochemical Development: Serves as an intermediate in the research and synthesis of new-generation pesticides and herbicides.
• Academic & Industrial R&D: Essential for exploratory chemistry in universities and corporate R&D labs focusing on isoquinoline derivatives.

Basic Information

Product Name	1-(4-Chloro-7-(Phenylthio)Isoquinolin-1-Yl)Guanidine Hydrochloride
CAS No.	223671-08-7
Molecular Formula	C₁₆H₁₄Cl₂N₄S
Molecular Weight	365.28 g/mol
Synonyms	1-(4-Chloro-7-(Phenylthio)-1-isoquinolinyl)guanidine hydrochloride; 1-(4-Chloro-7-(Phenylmercapto)isoquinolin-1-yl)guanidine HCl; Guanidine, N-[4-chloro-7-(phenylthio)-1-isoquinolinyl]-, monohydrochloride; 223671-08-7; 4-Chloro-7-(phenylthio)-1-isoquinolinamine, N-(diaminomethylene)-, hydrochloride; N-(4-Chloro-7-(phenylthio)-1-isoquinolinyl)guanidine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(4-Chloro-7-(Phenylthio)Isoquinolin-1-Yl)Guanidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry, inert conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.