Description

1-Guanidino-4-Chloro-7-Sulfamoyl-Isoquinoline Hydrochloride is a high-purity, functionalized isoquinoline derivative of significant interest in advanced chemical synthesis. This compound serves as a critical building block and intermediate for the development of novel pharmaceutical agents and bioactive molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for drug discovery programs and the synthesis of specialized chemical libraries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential therapeutic agents, particularly those targeting enzyme inhibition or receptor modulation.
• Chemical Biology Research: Used as a molecular probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as an intermediate in the research and synthesis of new crop protection agents and pesticides.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.
• Academic & Contract Research: Utilized in university and CRO laboratories for novel heterocyclic chemistry research and method development.

Basic Information

Product Name	1-Guanidino-4-Chloro-7-Sulfamoyl-Isoquinoline Hydrochloride
CAS No.	223671-03-2
Molecular Formula	C10H10ClN5O2S • HCl
Molecular Weight	328.61 g/mol (Free base: 291.73 g/mol)
Synonyms	1-Guanidino-4-chloro-7-sulfamoylisoquinoline hydrochloride; 4-Chloro-1-guanidino-7-sulfamoylisoquinoline HCl; 7-Sulfamoyl-1-guanidino-4-chloroisoquinoline hydrochloride; CAS 223671-03-2; 1-Amino-4-chloro-7-sulfamoylisoquinoline-2-carboximidamide hydrochloride; 4-Chloro-7-sulfamoyl-1-(diaminomethylideneamino)isoquinoline hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Guanidino-4-Chloro-7-Sulfamoyl-Isoquinoline Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates, and specifications can be aligned with client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.