Description

1-Guanidino-4-Chloro-7-Sulfamoyl-Isoquinoline is a high-purity, synthetically derived isoquinoline derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and pharmacophore for the design of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of new drug candidates targeting complex biological pathways.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel small-molecule drugs.
• Biochemical Research: Used as a tool compound in enzymatic and receptor-binding studies to investigate biological mechanisms.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• API Development: Investigated for its potential incorporation into Active Pharmaceutical Ingredients (APIs) for various therapeutic areas.
• High-Throughput Screening: Employed in compound libraries for the identification of new hits in drug discovery campaigns.

Basic Information

Product Name	1-Guanidino-4-Chloro-7-Sulfamoyl-Isoquinoline
CAS No.	223671-02-1
Molecular Formula	C10H9ClN4O2S
Molecular Weight	284.72 g/mol
Synonyms	4-Chloro-1-guanidino-7-sulfamoylisoquinoline; 7-Sulfamoyl-4-chloro-1-guanidinoisoquinoline; 1-Guanidino-4-chloro-7-sulfamoyl-isoquinoline; 223671-02-1; 4-Chloro-1-guanidino-7-sulfamoyl-isoquinoline; 1-(Diaminomethylideneamino)-4-chloro-7-sulfamoylisoquinoline
EINECS	Contact for details

Quality Control

Our 1-Guanidino-4-Chloro-7-Sulfamoyl-Isoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.