Description

Cyclohexanethiol,2-(1-Methylethyl)-,(1R,2R)-Rel-(9Ci) is a high-purity, chiral thiol derivative of isopropylcyclohexane, identified by CAS number 223653-39-2. This compound serves as a critical chiral building block and ligand precursor in advanced organic synthesis, where its stereochemistry and thiol functionality are essential for creating specific molecular architectures. It is particularly valuable for researchers and manufacturers in the pharmaceutical and fine chemical industries developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Catalyst & Ligand Synthesis: Used as a precursor for synthesizing chiral ligands and organocatalysts for asymmetric hydrogenation and other catalytic transformations.
• Agrochemical Research: Employed in the development of novel, stereospecific pesticides and herbicides.
• Fine Chemical Production: Serves as a building block for high-value specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Material Science: Potential monomer or modifier in the synthesis of polymers with unique properties due to the thiol group.
• Chemical Research & Development: A valuable reference standard and reagent in academic and industrial R&D for exploring new synthetic methodologies.

Basic Information

Product Name	Cyclohexanethiol,2-(1-Methylethyl)-,(1R,2R)-Rel-(9Ci)
CAS No.	223653-39-2
Molecular Formula	C9H18S
Molecular Weight	158.30 g/mol
Synonyms	(1R,2R)-2-Isopropylcyclohexanethiol; rel-(1R,2R)-2-(1-Methylethyl)cyclohexanethiol; (1R,2R)-2-(Propan-2-yl)cyclohexane-1-thiol; 2-Isopropylcyclohexanethiol (stereoisomer); Chiral 2-Isopropylcyclohexanethiol; (1R,2R)-rel-2-Isopropylcyclohexanethiol
EINECS	Contact for details

Quality Control

Our production of Cyclohexanethiol,2-(1-Methylethyl)-,(1R,2R)-Rel-(9Ci) adheres to stringent quality management protocols. Each batch is characterized and tested to ensure high chemical purity, correct stereochemistry, and consistent performance. Certificates of Analysis (COA) detailing identity (IR, NMR), chiral purity (Chiral HPLC or GC), chemical assay, and impurity profiles are provided with every shipment. We support cGMP and ISO 9001 standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, well-ventilated area. This material is easily oxidized and moisture-sensitive; prolonged exposure to air should be avoided. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral GC/HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.