Description

5-(1-Methyl-5-(Trifluoromethyl)-1H-Pyrazol-3-Yl)Thiophene-2-Carboxylic Acid is a high-value, multifunctional heterocyclic building block designed for advanced chemical synthesis. Its unique molecular architecture, featuring both a pyrazole and a thiophene ring, makes it a critical intermediate for developing novel active compounds. This product is essential for research and development teams in the pharmaceutical and agrochemical sectors seeking to create new molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl and heterocyclic components contribute to biological activity and environmental stability.
• Material Science Research: Acts as a precursor for functionalized monomers or ligands in the synthesis of advanced polymers, organic semiconductors, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed as a scaffold or tagging agent in the design of molecular probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	5-(1-Methyl-5-(Trifluoromethyl)-1H-Pyrazol-3-Yl)Thiophene-2-Carboxylic Acid
CAS No.	223499-20-5
Molecular Formula	C10H7F3N2O2S
Molecular Weight	276.24 g/mol
Synonyms	5-(1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 5-[1-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]-; 5-(1-Methyl-5-trifluoromethyl-1H-pyrazol-3-yl)thiophene-2-carboxylic acid; 5-(1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)-2-thiophenecarboxylic acid; 5-(1-Methyl-5-(trifluoromethyl)pyrazol-3-yl)thiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(1-Methyl-5-(Trifluoromethyl)-1H-Pyrazol-3-Yl)Thiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.