Description

Ethyl-1,1-D2-Methylamine is a deuterated analog of ethylmethylamine, specifically labeled at the 1,1-positions of the ethyl group. This isotopic labeling makes it a critical tool for mechanistic studies and metabolic pathway tracing in advanced research and development. It is primarily utilized by scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise isotopic markers for analytical and synthetic applications.

Application

• Pharmaceutical Research: Used as a deuterated building block in the synthesis of isotopically labeled Active Pharmaceutical Ingredients (APIs) for drug metabolism and pharmacokinetics (DMPK) studies.
• Analytical Chemistry: Serves as an internal standard or reference material in quantitative mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy to improve analytical accuracy.
• Mechanistic Studies: Employed in reaction mechanism elucidation, where the deuterium atoms act as tracers to follow the fate of specific molecular fragments.
• Agrochemical Development: Used in the synthesis of labeled pesticide or herbicide intermediates to study environmental degradation and metabolic pathways in plants.
• Material Science: Potential precursor for the synthesis of specialty polymers or organic electronic materials where isotopic purity can influence physical properties.
• Catalysis Research: Applied in kinetic isotope effect (KIE) studies to investigate catalytic reaction pathways and transition states.

Basic Information

Product Name	Ethyl-1,1-D2-Methylamine
CAS No.	223459-63-0
Molecular Formula	C3H7D2N
Molecular Weight	61.12 g/mol
Synonyms	N-Methyl-1,1-dideuteroethylamine; N-Methylethylamine-1,1-d2; 1,1-Dideutero-N-methylethylamine; Ethyl(methyl)amine-1,1-d2; (1,1-Dideuteroethyl)(methyl)amine; N-Ethyl-N-methylamine-d2 (specific to this isomer); Deuterated ethylmethylamine; EMA-d2
EINECS	Contact for details

Quality Control

Our Ethyl-1,1-D2-Methylamine is produced under controlled conditions to ensure high isotopic and chemical purity, meeting the stringent requirements of research and development. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment (D-content), chemical purity by GC or HPLC, and identity confirmation by spectroscopic methods. We adhere to a rigorous quality management system to ensure batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place, ideally at 2-8°C for long-term stability. The container should be kept upright and sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation and moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Purity (GC / HPLC)	≥ 98.0%
Isotopic Enrichment (D-content)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.