Description

Diethyl 3,5-Dimethoxybenzylphosphonate is a high-purity organophosphorus compound, specifically a benzylphosphonate derivative, serving as a critical synthetic intermediate. Its primary value lies in its role as a versatile building block for constructing complex molecules, particularly in the synthesis of fine chemicals and active pharmaceutical ingredients (APIs). This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, including kinase inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized phosphonate-based ligands used in catalysis.
• Material Science Research: Employed in the creation of functionalized organic frameworks and specialty polymers.
• Chemical Biology Probes: Utilized to develop phosphonate-containing probes for studying enzymatic activity and metabolic pathways.
• Academic & Industrial R&D: A fundamental reagent for method development and exploratory organic synthesis in laboratory settings.

Basic Information

Product Name	Diethyl 3,5-Dimethoxybenzylphosphonate
CAS No.	223386-36-5
Molecular Formula	C13H21O5P
Molecular Weight	288.28 g/mol
Synonyms	Diethyl (3,5-Dimethoxybenzyl)phosphonate; (3,5-Dimethoxybenzyl)phosphonic Acid Diethyl Ester; Diethyl (3,5-Dimethoxyphenylmethyl)phosphonate; Phosphonic Acid, P-[(3,5-Dimethoxyphenyl)methyl]-, Diethyl Ester; 3,5-Dimethoxybenzylphosphonic Acid Diethyl Ester; Diethyl 3,5-Dimethoxybenzylphosphonic Acid Ester; Benzylphosphonate Derivative CAS 223386-36-5
EINECS	Contact for details

Quality Control

Our Diethyl 3,5-Dimethoxybenzylphosphonate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, including cGMP-compliant pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.