Description

D,L--2-Methoxy-α-Methylbenzyl Bromide is a versatile chiral building block and alkylating agent of significant interest in advanced organic synthesis. Its value lies in its ability to introduce a methoxy-substituted benzyl moiety, a key structural feature for modulating the physicochemical properties of target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and complex specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of chiral drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the specific stereochemistry influences biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized monomers or additives for specialty polymers with tailored properties.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including new alkylation and cross-coupling reactions.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fragrance and flavor ingredients.

Basic Information

Product Name	D,L--2-Methoxy-α-Methylbenzyl Bromide
CAS No.	223375-01-7
Molecular Formula	C10H13BrO
Molecular Weight	229.11 g/mol
Synonyms	α-Bromo-2-methoxy-α-methyltoluene; (RS)-1-(2-Methoxyphenyl)ethyl bromide; 1-Bromo-1-(2-methoxyphenyl)ethane; dl-2-Methoxy-α-methylbenzyl bromide; (±)-1-(2-Methoxyphenyl)ethyl bromide; 2-Methoxy-α-methylbenzyl bromide; 1-(2-Methoxyphenyl)ethyl bromide
EINECS	Contact for details

Quality Control

Our D,L--2-Methoxy-α-Methylbenzyl Bromide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, enantiomeric ratio (if applicable), and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. Due to its light-sensitive nature and reactivity, it is recommended to handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if enantiopure)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.