Description

2-Methylpropionic-D7 Acid is a high-purity, deuterium-labeled isotopologue of isobutyric acid, specifically designed for advanced analytical and research applications. This compound is essential for use as an internal standard in quantitative mass spectrometry, enabling precise and accurate measurements in complex matrices. It is primarily utilized by analytical chemists and researchers in the pharmaceutical, agrochemical, and environmental testing industries for method development, metabolic studies, and trace-level quantification.

Application

• Internal Standard for Mass Spectrometry (MS): Used in LC-MS and GC-MS for the accurate quantification of isobutyric acid and related metabolites in biological and environmental samples.
• Metabolic Pathway Tracing: Employed in pharmacokinetic and metabolomic studies to track and elucidate biochemical pathways using deuterium labeling.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities and degradation products in drug substances.
• Environmental Analysis: Facilitates the detection and measurement of volatile fatty acids in water, soil, and industrial waste streams.
• Chemical Synthesis Intermediate: Serves as a labeled building block for the synthesis of more complex deuterated compounds for research purposes.
• NMR Spectroscopy: Used as a solvent or reference compound in nuclear magnetic resonance studies due to its distinct spectral properties.

Basic Information

Product Name	2-Methylpropionic-D7 Acid
CAS No.	223134-74-5
Molecular Formula	C4D7HO2
Molecular Weight	91.15 g/mol
Synonyms	Isobutyric-d7 Acid; (2H7)-2-Methylpropanoic Acid; Deuterated Isobutyric Acid; Perdeuterated Isobutyric Acid; 2-Methylpropanoic-2,2-d2 Acid (3,3,3-d3); Isobutyric-2,2-d2 Acid (3,3,3-d3); Isobutanoic-d7 Acid
EINECS	Contact for details

Quality Control

Every batch of 2-Methylpropionic-D7 Acid is manufactured and tested under strict quality management systems to ensure the highest isotopic and chemical purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing isotopic enrichment, chemical purity, and solvent residue are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.