Description

5-tert-Butyltryptamine is a specialized tryptamine derivative characterized by the presence of a bulky tert-butyl substituent on the indole ring. This structural modification makes it a valuable advanced pharmaceutical intermediate and a crucial building block in medicinal chemistry research. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical and biotechnology sectors for the synthesis of novel therapeutic agents targeting the central nervous system.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel serotonin receptor modulators and other neuroactive compounds.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Biochemical Tool Compound: Used in neuroscience research to study tryptaminergic pathways and receptor interactions.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	5-tert-Butyltryptamine
CAS No.	222733-86-0
Molecular Formula	C₁₅H₂₂N₂
Molecular Weight	230.35 g/mol
Synonyms	5-tert-Butyl-1H-indole-3-ethanamine; 2-(5-tert-Butyl-1H-indol-3-yl)ethan-1-amine; 5-tert-Butylindole-3-ethylamine; 5-tert-Butyltryptamine; 5-tert-Butyl-3-(2-aminoethyl)indole; 5-(tert-Butyl)tryptamine
EINECS	Contact for details

Quality Control

Our 5-tert-Butyltryptamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.