Description

1-(2-Bromophenyl)-2-Propyn-1-Ol is a specialized organic building block featuring both a bromoaryl and a propargylic alcohol functional group. This unique bifunctional structure makes it a valuable intermediate for constructing complex molecules in advanced synthetic chemistry. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as cross-coupling reactions and the synthesis of novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for constructing complex molecular architectures.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and fungicides, leveraging its reactive sites for structural diversification.
• Material Science Research: Serves as a monomer or building block for developing advanced polymers and functional materials with specific optical or electronic properties.
• Cross-Coupling Reactions: The bromophenyl moiety is an effective handle for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira), while the propargylic alcohol can undergo further transformations.
• Academic & R&D Laboratories: Employed in methodological studies and the discovery of new synthetic pathways in organic chemistry.
• Ligand and Catalyst Development: Useful for synthesizing specialized ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	1-(2-Bromophenyl)-2-Propyn-1-Ol
CAS No.	222713-56-6
Molecular Formula	C9H7BrO
Molecular Weight	211.06 g/mol
Synonyms	2-Bromophenyl propargyl alcohol; (2-Bromophenyl)(prop-2-yn-1-yl) alcohol; 1-(2-Bromophenyl)prop-2-yn-1-ol; 2-Bromobenzeneethanol, α-ethynyl-; α-Ethynyl-2-bromobenzyl alcohol; Propargyl alcohol, 2-bromophenyl-; 2-Bromophenyl(2-propynyl) alcohol; 2-Bromo-α-ethynylbenzyl alcohol
EINECS	Contact for details

Quality Control

Our 1-(2-Bromophenyl)-2-Propyn-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.