Description

5H-1,3-Dioxolo4,5-Cpyrrole-5-Carboxylic Acid, 4-4-Amino-5-(Ethoxycarbonyl)-1H-Pyrrol-3-Yltetrahydro-2,2,6-Trimethyl-, 1,1-Dimethylethyl Ester, (3As,4S,6R,6Ar)- is a high-purity, complex heterocyclic building block of significant interest in advanced organic synthesis. Its intricate molecular architecture, featuring fused dioxolane and pyrrole rings with multiple chiral centers, makes it a critical intermediate for constructing sophisticated pharmacologically active molecules. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of advanced, high-specificity pesticides and herbicides, leveraging its complex stereochemistry.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex natural product analogs and novel heterocyclic compounds.
• Process Chemistry Development: Acts as a standard or reference material for scaling up synthetic routes in pilot plants and manufacturing.
• Material Science Research: Investigated as a precursor for specialty polymers or organic electronic materials due to its conjugated system potential.

Basic Information

Product Name	5H-1,3-Dioxolo4,5-Cpyrrole-5-Carboxylic Acid, 4-4-Amino-5-(Ethoxycarbonyl)-1H-Pyrrol-3-Yltetrahydro-2,2,6-Trimethyl-, 1,1-Dimethylethyl Ester, (3As,4S,6R,6Ar)-
CAS No.	222631-39-2
Molecular Formula	C20H30N2O6
Molecular Weight	394.47 g/mol
Synonyms	(3aR,4S,6R,6aR)-4-(4-Amino-5-ethoxycarbonyl-1H-pyrrol-3-yl)tetrahydro-2,2,6-trimethyl-5H-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylic acid tert-butyl ester; tert-Butyl (3aR,4S,6R,6aR)-4-(4-amino-5-(ethoxycarbonyl)-1H-pyrrol-3-yl)-2,2,6-trimethyltetrahydro-5H-[1,3]dioxolo[4,5-c]pyrrole-5-carboxylate; CAS 222631-39-2; 5H-[1,3]Dioxolo[4,5-c]pyrrole-5-carboxylic acid, 4-[4-amino-5-(ethoxycarbonyl)-1H-pyrrol-3-yl]tetrahydro-2,2,6-trimethyl-, 1,1-dimethylethyl ester, (3aR,4S,6R,6aR)-; Advanced Pyrrole-Dioxolane Ester Intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through modern analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider using an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.