Description

5-Amino-6-Chloro (1H)Indazole is a high-purity, versatile heterocyclic building block of significant importance in advanced organic synthesis. Its value lies in its functionalized indazole core, which serves as a critical scaffold for constructing complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, activity-based probes (ABPs), and photoaffinity labels for target identification and validation.
• Material Science: Serves as a monomer or functionalizing agent in the development of advanced polymers and organic electronic materials.
• Contract Research & Development (CRO/CMO): Supplied to research organizations and custom synthesis facilities for client-directed projects.
• Academic Research: Utilized in university and institutional labs for methodological development and exploratory synthesis of novel heterocyclic compounds.

Basic Information

Product Name	5-Amino-6-Chloro (1H)Indazole
CAS No.	221681-75-0
Molecular Formula	C7H6ClN3
Molecular Weight	167.60 g/mol
Synonyms	6-Chloro-1H-indazol-5-amine; 5-Amino-6-chloro-1H-indazole; 6-Chloro-5-aminoindazole; 1H-Indazole, 5-amino-6-chloro-; 5-Amino-6-chloroindazole; 6-Chloro-1H-indazol-5-ylamine; (1H)-Indazole, 5-amino-6-chloro-
EINECS	Contact for details

Quality Control

Our 5-Amino-6-Chloro (1H)Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full batch traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.