Description

(R)-4-(1-Aminoethyl)Phenol is a chiral aromatic amine derivative of significant importance in asymmetric synthesis. This compound serves as a versatile and high-value chiral building block for the pharmaceutical and fine chemical industries. It is particularly sought after by research and development teams for the synthesis of active pharmaceutical ingredients (APIs), chiral ligands, and advanced intermediates requiring a specific stereochemical configuration.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of enantiomerically pure drugs, particularly in cardiovascular and central nervous system (CNS) therapeutic areas.
• Asymmetric Catalyst Ligand Precursor: Used in the synthesis of chiral ligands for transition metal catalysis, enabling highly selective chemical transformations.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules for agrochemicals and specialty materials.
• Biochemical Research: Utilized as a standard or reagent in studies involving chiral recognition, enzyme inhibition, and receptor binding assays.
• Material Science: Potential precursor for chiral polymers or functionalized surfaces with specific optical properties.

Basic Information

Product Name	(R)-4-(1-Aminoethyl)Phenol
CAS No.	221670-72-0
Molecular Formula	C8H11NO
Molecular Weight	137.18 g/mol
Synonyms	(R)-1-(4-Hydroxyphenyl)ethylamine; (R)-4-(1-Aminoethyl)phenol; (R)-p-(1-Aminoethyl)phenol; (R)-4-Hydroxy-α-methylbenzylamine; (R)-HMPA; (R)-1-(4-Hydroxyphenyl)ethanamine; (R)-(-)-4-(1-Aminoethyl)phenol; (R)-4-(α-Aminoethyl)phenol
EINECS	Contact for details

Quality Control

Our (R)-4-(1-Aminoethyl)Phenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.