Description

1-[(tert-Butyl)Oxycarbonyl]-4-Phenylpyrroline-3-Carboxylic Acid is a high-purity, protected amino acid derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and bioactive compounds. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in peptide mimetics and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for non-standard amino acid incorporation.
• Peptidomimetic Synthesis: Used to create peptide analogs and mimetics with enhanced metabolic stability and bioavailability for drug discovery.
• Medicinal Chemistry: Serves as a versatile scaffold for constructing focused libraries and exploring structure-activity relationships (SAR) in lead optimization.
• Agrochemical Research: Employed in the synthesis of novel compounds with potential herbicidal or insecticidal activity.
• Academic & Contract Research: A valuable reagent for methodology development and complex natural product synthesis in academic and CRO (Contract Research Organization) settings.
• Bioconjugation Chemistry: Potential use in creating linkers or modified biomolecules for bioconjugation and probe development.

Basic Information

Product Name	1-[(tert-Butyl)Oxycarbonyl]-4-Phenylpyrroline-3-Carboxylic Acid
CAS No.	221142-28-5
Molecular Formula	C₁₆H₁₉NO₄
Molecular Weight	289.33 g/mol
Synonyms	Boc-4-Phenyl-δ³-pyrroline-3-carboxylic Acid; 1-Boc-4-phenyl-3-pyrroline-3-carboxylic acid; 3-Pyrroline-3-carboxylic acid, 1-[(1,1-dimethylethoxy)carbonyl]-4-phenyl-; 4-Phenyl-1-((tert-butoxy)carbonyl)-2,5-dihydro-1H-pyrrole-3-carboxylic acid; tert-Butyl 3-carboxy-4-phenyl-2,5-dihydro-1H-pyrrole-1-carboxylate; N-Boc-4-phenyl-3-pyrroline-3-carboxylic acid; 1-N-Boc-4-phenyl-3-pyrroline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-[(tert-Butyl)Oxycarbonyl]-4-Phenylpyrroline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.