Description

2-Bromo-5-Methyl-3-Thiophenecarboxylic Acid is a high-value heterocyclic building block essential for advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and functional materials. It is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its functionalized thiophene core.
• Material Science: Serves as a precursor for organic electronic materials, such as conductive polymers and organic semiconductors, due to the thiophene moiety.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for creating labeled compounds or probes for studying biological mechanisms and interactions.
• Custom Synthesis & Scale-Up: A critical starting material for contract research and manufacturing organizations (CROs/CMOs) engaged in custom synthesis projects.

Basic Information

Product Name	2-Bromo-5-Methyl-3-Thiophenecarboxylic Acid
CAS No.	221061-14-9
Molecular Formula	C7H5BrO2S
Molecular Weight	233.08 g/mol
Synonyms	5-Methyl-2-bromothiophene-3-carboxylic acid; 2-Bromo-5-methylthiophene-3-carboxylic acid; 3-Thiophenecarboxylic acid, 2-bromo-5-methyl-; 2-Bromo-5-methyl-3-thiophenecarboxylate; 221061-14-9; 2-Bromo-5-methylthiophene-3-carboxylate; 5-Methyl-2-bromo-3-thiophenecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Methyl-3-Thiophenecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support cGMP compliance for advanced intermediates and can tailor quality protocols to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.