Description

(2-Iodo-5-Methylphenyl)Methanol is a versatile iodinated aromatic alcohol building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a reactive benzylic alcohol group and an iodine substituent, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging the iodine atom for further functionalization.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis, such as palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of advanced polymers and liquid crystals with specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	(2-Iodo-5-Methylphenyl)Methanol
CAS No.	220991-50-4
Molecular Formula	C8H9IO
Molecular Weight	248.06 g/mol
Synonyms	2-Iodo-5-methylbenzyl alcohol; (2-Iodo-5-methylphenyl)methanol; 5-Methyl-2-iodobenzyl alcohol; 1-(Hydroxymethyl)-2-iodo-5-methylbenzene; α-Hydroxy-2-iodo-5-methyltoluene; 2-Iodo-5-methylbenzenemethanol; Benzenemethanol, 2-iodo-5-methyl-
EINECS	Contact for details

Quality Control

Our (2-Iodo-5-Methylphenyl)Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability, consistency, and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.