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Robenacoxib CAS NO 220991-32-2
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CAS No.:220991-32-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Robenacoxib is a highly selective non-steroidal anti-inflammatory drug (NSAID) belonging to the coxib class, specifically designed for veterinary use. Its primary value lies in its potent and targeted inhibition of the COX-2 enzyme, providing effective pain relief and anti-inflammatory action with a reduced risk of gastrointestinal side effects compared to non-selective NSAIDs. This makes it an essential active pharmaceutical ingredient (API) for manufacturers developing veterinary pharmaceuticals, particularly for companion animals like dogs and cats, to manage post-operative pain and chronic inflammatory conditions.
Application
Robenacoxib is a critical component in the formulation of modern veterinary medicines. Its primary and specialized applications include:
- Veterinary Pharmaceutical API: Core active ingredient in injectable solutions and oral tablets for dogs and cats.
- Post-Operative Pain Management: Formulated for controlling pain following surgical procedures in companion animals.
- Chronic Osteoarthritis Treatment: Used in medications designed for long-term management of joint inflammation and pain.
- Anti-inflammatory Formulations: Serves as the key therapeutic agent in anti-inflammatory drugs for soft tissue injuries.
- Veterinary Generic Drug Production: Sourced by manufacturers producing generic versions of approved robenacoxib-based medications.
- Veterinary Drug R&D: Used in research and development of new analgesic and anti-inflammatory veterinary products.
Basic Information
| Product Name | Robenacoxib |
| CAS No. | 220991-32-2 |
| Molecular Formula | C₁₆H₁₄F₃N₃O₃S |
| Molecular Weight | 385.36 g/mol |
| Synonyms | Robenacoxib; UNII-8HJC48039W; 4-[4-(4-Methylthiophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide; Onsior (Trade Name); AHR-1478; Vetprofen (associated); COX-2 Inhibitor (Veterinary); Selective NSAID (Veterinary) |
| EINECS | Contact for details |
Quality Control
Our Robenacoxib is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. We provide full traceability and support our clients with regulatory documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory submissions.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to protect contents from moisture. Keep away from incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to reference spectrum |
| Identification (HPLC) | Retention time corresponds to reference standard |
| Assay (HPLC) | 98.0% - 102.0% (on anhydrous basis) |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
| Related Substances (HPLC) | Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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