Description

tert-Butyl 2-(1-benzyl-2-ethyl-1H-indol-4-yloxy)acetate is a specialized indole derivative ester, serving as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by fine chemical manufacturers and R&D laboratories engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the indole scaffold for biological activity.
• Material Science: Serves as a precursor for functionalized polymers and advanced organic materials with specific electronic or photonic properties.
• Academic & Contract Research: Employed in university and CRO settings for methodological studies in heterocyclic and medicinal chemistry.
• Custom Synthesis: A starting material for the bespoke production of complex molecules for client-specific applications.

Basic Information

Product Name	tert-Butyl 2-(1-benzyl-2-ethyl-1H-indol-4-yloxy)acetate
CAS No.	220862-18-0
Molecular Formula	C23H27NO3
Molecular Weight	365.47 g/mol
Synonyms	tert-Butyl (1-benzyl-2-ethyl-1H-indol-4-yloxy)acetate; 2-(1-Benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid tert-butyl ester; 4-[(tert-Butoxycarbonyl)methoxy]-1-benzyl-2-ethylindole; 1-Benzyl-2-ethyl-4-[(2-tert-butoxy-2-oxoethoxy)]-1H-indole; 220862-18-0; TBEA Intermediate; BzEt-Indole-OAc-OtBu
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 2-(1-benzyl-2-ethyl-1H-indol-4-yloxy)acetate adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.