Description

5,7-Difluoro-2-Indolecarboxylic Acid Ethyl Ester is a high-purity fluorinated indole derivative, a crucial building block in modern organic synthesis. Its value lies in its role as a versatile synthon for constructing complex heterocyclic compounds, particularly in pharmaceutical research. This product is essential for medicinal chemists and R&D laboratories focused on developing new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging the biological activity of the fluorinated indole scaffold.
• Material Science: Serves as a monomer or building block for creating specialty polymers and organic electronic materials with unique optoelectronic properties.
• Chemical Biology: Employed as a probe or labeled compound in biochemical assays and diagnostic research due to its fluorinated structure.
• Academic & Contract Research: A fundamental reagent for synthetic methodology development and exploratory chemistry in university and CRO laboratories.

Basic Information

Product Name	5,7-Difluoro-2-Indolecarboxylic Acid Ethyl Ester
CAS No.	220679-10-7
Molecular Formula	C11H9F2NO2
Molecular Weight	225.19 g/mol
Synonyms	Ethyl 5,7-Difluoro-1H-indole-2-carboxylate; 5,7-Difluoroindole-2-carboxylic Acid Ethyl Ester; 2-Carbethoxy-5,7-difluoroindole; 1H-Indole-2-carboxylic acid, 5,7-difluoro-, ethyl ester; Ethyl 5,7-difluoroindole-2-carboxylate
EINECS	Contact for details

Quality Control

Our 5,7-Difluoro-2-Indolecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.