Description

Methyl 3-Bromo-1H-Indole-2-Carboxylate is a versatile brominated indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its reactive bromine substituent and ester functionality, enabling precise molecular construction. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex indole-based drug candidates, including kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and plant growth regulators that leverage the indole scaffold.
• Material Science: Serves as a precursor for organic semiconductors, dyes, and photochromic materials due to its conjugated system.
• Academic & R&D: Essential reagent in methodological studies for cross-coupling reactions, such as Suzuki-Miyaura and Buchwald-Hartwig aminations.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.

Basic Information

Product Name	Methyl 3-Bromo-1H-Indole-2-Carboxylate
CAS No.	220664-31-3
Molecular Formula	C10H8BrNO2
Molecular Weight	254.08 g/mol
Synonyms	3-Bromo-1H-indole-2-carboxylic acid methyl ester; Methyl 3-bromoindole-2-carboxylate; 3-Bromoindole-2-carboxylic acid methyl ester; 2-Carbomethoxy-3-bromoindole; 1H-Indole-2-carboxylic acid, 3-bromo-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-1H-Indole-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.