Description

5-(Pyrrolidine-1-Sulfonyl)-1H-Indole-2,3-Dione is a specialized heterocyclic building block and synthetic intermediate of significant interest in advanced organic synthesis. This compound, with CAS number 220510-17-8, is valued for its unique molecular architecture, which combines an isatin core with a pyrrolidine sulfonyl moiety, enabling diverse chemical transformations. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and enzyme inhibition.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive scaffold.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic systems and functionalized indole derivatives for material science and catalysis.
• Biochemical Probe Development: Acts as a starting material for creating molecular probes to study biological pathways and protein interactions.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological studies and discovery chemistry.

Basic Information

Product Name	5-(Pyrrolidine-1-Sulfonyl)-1H-Indole-2,3-Dione
CAS No.	220510-17-8
Molecular Formula	C₁₂H₁₂N₂O₄S
Molecular Weight	280.30 g/mol
Synonyms	5-(1-Pyrrolidinylsulfonyl)isatin; 5-(Pyrrolidine-1-sulfonyl)isatin; 1H-Indole-2,3-dione, 5-(1-pyrrolidinylsulfonyl)-; 5-Pyrrolidin-1-ylsulfonyl-1H-indole-2,3-dione; Isatin, 5-(pyrrolidin-1-ylsulfonyl)-; 220510-17-8; 5-(N-Pyrrolidinylsulfonyl)isatin
EINECS	Contact for details

Quality Control

Our 5-(Pyrrolidine-1-Sulfonyl)-1H-Indole-2,3-Dione is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, for comprehensive characterization and purity verification. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.