Description

1-tert-Butyl 4-Methyl 1H-Indole-1,4-Dicarboxylate is a high-purity, protected indole derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly those containing indole or heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and pesticides that require specific indole-based structures.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor in the synthesis of specialized organic semiconductors and emissive layer materials.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Academic and Industrial Research: A versatile reagent for methodological studies in organic chemistry and the exploration of new synthetic pathways.
• Fine Chemical Production: Used in the multi-step synthesis of complex, high-value specialty chemicals and dyes.

Basic Information

Product Name	1-tert-Butyl 4-Methyl 1H-Indole-1,4-Dicarboxylate
CAS No.	220499-11-6
Molecular Formula	C15H17NO4
Molecular Weight	275.30 g/mol
Synonyms	1H-Indole-1,4-dicarboxylic acid, 1-(1,1-dimethylethyl) 4-methyl ester; 1-tert-Butoxycarbonyl-4-methoxycarbonylindole; 1-Boc-4-COOMe-indole; tert-Butyl 4-(methoxycarbonyl)-1H-indole-1-carboxylate; Methyl 1-(tert-butoxycarbonyl)-1H-indole-4-carboxylate; 1-(tert-Butoxycarbonyl)indole-4-carboxylic acid methyl ester; 1-Boc-indole-4-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 4-Methyl 1H-Indole-1,4-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.