Description

2-Bromo-3-Chlorobenzyl Bromide is a versatile and highly reactive benzyl halide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce both bromine and chlorine functional groups, enabling precise molecular construction for complex target compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where the benzyl bromide moiety acts as a reactive handle for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphine ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, or polymers with specific halogen-substituted aromatic units.
• Cross-Coupling Reactions: An effective substrate for various palladium-catalyzed cross-coupling reactions, such as Suzuki or Negishi couplings, to form biaryl structures.
• Chemical Biology Probes: Useful for synthesizing molecular probes where the benzyl bromide group can be used for selective labeling or bioconjugation.

Basic Information

Product Name	2-Bromo-3-Chlorobenzyl Bromide
CAS No.	220453-60-1
Molecular Formula	C7H5Br2Cl
Molecular Weight	284.38 g/mol
Synonyms	1-(Bromomethyl)-2-bromo-3-chlorobenzene; 2-Bromo-3-chloro-α,α-dibromotoluene; (2-Bromo-3-chlorophenyl)methyl bromide; α-Bromo-2-bromo-3-chlorotoluene; Benzene, 1-(bromomethyl)-2-bromo-3-chloro-; 3-Chloro-2-bromobenzyl bromide
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Chlorobenzyl Bromide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.