Description

Bicyclo[2.2.2]Oct-5-Ene-2,3-Dione, 7-Ethoxy-5-Ethyl-, (1R,4R,7R)-Rel- (9Ci) is a high-purity, stereochemically defined bicyclic dione derivative, serving as a critical chiral building block and advanced intermediate in sophisticated organic synthesis. Its rigid, functionalized structure is engineered to impart precise stereochemical control and specific reactivity in the construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-fidelity intermediates for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery programs.
• Agrochemical Synthesis: Used as a building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators with enhanced efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a core structure for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Advanced Material Research: Intermediate in the production of specialty polymers and organic electronic materials where the rigid bicyclic framework contributes to desired material properties.
• Academic & R&D: A valuable tool for methodological studies in organic chemistry, enabling research into new cycloaddition and functionalization reactions.
• Fine Chemical Production: Employed in the custom synthesis of high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.2]Oct-5-Ene-2,3-Dione, 7-Ethoxy-5-Ethyl-, (1R,4R,7R)-Rel- (9Ci)
CAS No.	220304-93-8
Molecular Formula	C12H16O3
Molecular Weight	208.25 g/mol
Synonyms	7-Ethoxy-5-ethylbicyclo[2.2.2]oct-5-ene-2,3-dione, rel-(1R,4R,7R)-Isomer; (1R,4R,7R)-rel-7-Ethoxy-5-ethylbicyclo[2.2.2]oct-5-ene-2,3-dione; 5-Ethyl-7-ethoxybicyclo[2.2.2]oct-5-ene-2,3-dione; Bicyclo[2.2.2]oct-5-ene-2,3-dione, 7-ethoxy-5-ethyl-, (1R,4R,7R)-rel-; Ethyl Ethoxy Bicyclooctenedione; Chiral Bicyclic Dione Derivative
EINECS	Contact for details

Quality Control

Every batch of our Bicyclo[2.2.2]Oct-5-Ene-2,3-Dione derivative is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing purity, chiral excess, and impurity profiles is provided with each shipment, supporting cGMP and ISO standards for traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.