Description

Bicyclo[2.2.2]Oct-5-Ene-2,3-Dione, 5-Methyl-8-Propoxy-, (1R,4R,8R)-Rel- (9Ci) is a high-purity, stereochemically defined bicyclic dione derivative, serving as a critical chiral building block and synthetic intermediate. Its value lies in its rigid, three-dimensional molecular framework, which is essential for imparting specific stereochemistry and structural complexity in advanced organic syntheses. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as asymmetric catalysis and the synthesis of complex natural products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in developing central nervous system (CNS) and anti-inflammatory drugs.
• Asymmetric Catalysis Ligand Precursor: Used to construct sophisticated, enantiomerically pure ligands for transition metal catalysts in stereoselective reactions.
• Agrochemical Research: Serves as a building block for developing new chiral pesticides and herbicides with enhanced efficacy and environmental profiles.
• Advanced Material Synthesis: Employed in the creation of specialty polymers and organic electronic materials where a rigid, functionalized core structure is required.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry, enabling studies in cycloaddition reactions and stereochemical control.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing complex, naturally occurring odorants and flavor compounds with specific stereocenters.

Basic Information

Item	Detail
Product Name	Bicyclo[2.2.2]Oct-5-Ene-2,3-Dione, 5-Methyl-8-Propoxy-, (1R,4R,8R)-Rel- (9Ci)
CAS No.	220304-83-6
Molecular Formula	C12H16O3
Molecular Weight	208.25 g/mol
Synonyms	(1R,4R,8R)-5-Methyl-8-propoxybicyclo[2.2.2]oct-5-ene-2,3-dione; rel-(1R,4R,8R)-5-Methyl-8-propoxybicyclo[2.2.2]oct-5-ene-2,3-dione; 5-Methyl-8-propoxybicyclo[2.2.2]oct-5-ene-2,3-dione (rel-(1R,4R,8R)-form); Bicyclo[2.2.2]oct-5-ene-2,3-dione, 5-methyl-8-propoxy-, (1R,4R,8R)-rel-; 220304-83-6; Chiral Bicyclic Dione Derivative
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.2]Oct-5-Ene-2,3-Dione derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric purity and chemical identity. Certificates of Analysis (COA) detailing purity, chiral excess, and impurity profiles are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be sensitive to prolonged exposure to air and moisture; for long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.