Description

Bicyclo[2.2.2]Oct-5-Ene-2,3-Dione, 8-Ethoxy-5-Ethyl-, (1R,4R,8R)-Rel- (9Ci) is a high-purity, stereochemically defined bicyclic dione derivative, serving as a sophisticated chiral building block and synthetic intermediate. Its rigid, functionalized structure is critical for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily sought after by research and development teams in the pharmaceutical and advanced materials sectors for applications in asymmetric synthesis, ligand development, and the creation of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates and complex active pharmaceutical ingredients (APIs).
• Asymmetric Catalysis: Used in the development and synthesis of chiral ligands and organocatalysts for stereoselective reactions.
• Advanced Material Synthesis: Building block for creating specialized polymers, dendrimers, or organic frameworks with unique structural properties.
• Academic & Industrial R&D: Essential reagent for methodological development in organic chemistry and exploration of new reaction pathways.
• Agrochemical Research: Potential intermediate in the development of new, stereochemically pure crop protection agents.
• Fine Chemical Production: Employed in the custom synthesis of high-value, low-volume specialty chemicals for various industries.

Basic Information

Product Name	Bicyclo[2.2.2]Oct-5-Ene-2,3-Dione, 8-Ethoxy-5-Ethyl-, (1R,4R,8R)-Rel- (9Ci)
CAS No.	220304-76-7
Molecular Formula	C12H16O3
Molecular Weight	208.25 g/mol
Synonyms	8-Ethoxy-5-ethylbicyclo[2.2.2]oct-5-ene-2,3-dione, rel-(1R,4R,8R)-Isomer; (1R,4R,8R)-rel-8-Ethoxy-5-ethylbicyclo[2.2.2]oct-5-ene-2,3-dione; 5-Ethyl-8-ethoxybicyclo[2.2.2]oct-5-ene-2,3-dione; Bicyclo[2.2.2]oct-5-ene-2,3-dione, 8-ethoxy-5-ethyl-, (1R,4R,8R)-rel-; Ethyl Ethoxy Bicyclooctenedione; Chiral Bicyclic Dione Derivative
EINECS	Contact for details

Quality Control

We supply Bicyclo[2.2.2]Oct-5-Ene-2,3-Dione, 8-Ethoxy-5-Ethyl-, (1R,4R,8R)-Rel- (9Ci) with a strong commitment to quality and batch-to-batch consistency. Our products undergo rigorous analytical testing, including chiral HPLC, NMR, and mass spectrometry, to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each batch. Our quality system is designed to meet the stringent requirements of research and cGMP-grade manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.