Description

7-Iodo-1,2,3,4-Tetrahydro-Isoquinoline Hydrochloride is a halogenated tetrahydroisoquinoline derivative, a versatile and valuable building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting neurological and cardiovascular systems.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Suzuki, Sonogashira) and other transformations to introduce the iodinated tetrahydroisoquinoline scaffold.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new chemical entities for various therapeutic areas.
• Agrochemical Development: Acts as an intermediate in the research and synthesis of novel crop protection agents and pesticides.
• Chemical Biology Probe Synthesis: Utilized to create labeled compounds or probes for studying biological pathways and target engagement.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	7-Iodo-1,2,3,4-Tetrahydro-Isoquinoline Hydrochloride
CAS No.	220247-85-8
Molecular Formula	C9H10IN•HCl
Molecular Weight	295.55 g/mol
Synonyms	7-Iodo-1,2,3,4-tetrahydroisoquinoline hydrochloride; 7-Iodo-1,2,3,4-tetrahydroisoquinoline HCl; 1,2,3,4-Tetrahydro-7-iodoisoquinoline hydrochloride; 7-Iodo-1,2,3,4-tetrahydro-isoquinoline monohydrochloride; 7-Iodo-THIQ HCl; 7-Iodo-1,2,3,4-THIQ•HCl
EINECS	Contact for details

Quality Control

Our 7-Iodo-1,2,3,4-Tetrahydro-Isoquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key specifications such as assay and impurity profiles. Our commitment to quality supports your research and development needs with reliable, high-purity materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed in a dry environment. Recommended long-term storage at controlled room temperature (15-25°C).

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.