Description

7-Bromo-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is a versatile and high-purity organic building block essential for advanced chemical synthesis. Its value lies in providing a functionalized isoquinoline scaffold, crucial for constructing complex molecular architectures in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as medicinal chemistry and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological and cardiovascular disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating novel pesticides and herbicides with specific biological activity.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and biological pathways.
• Organic Synthesis: Acts as a brominated intermediate for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Academic Research: Employed in universities and research institutes for methodological development and the exploration of new heterocyclic chemistry.

Basic Information

Item	Details
Product Name	7-Bromo-1,2,3,4-Tetrahydroisoquinoline Hydrochloride
CAS No.	220247-73-4
Molecular Formula	C9H10BrN·HCl
Molecular Weight	248.55 g/mol
Synonyms	7-Bromo-1,2,3,4-tetrahydroisoquinoline HCl; 7-Bromo-1,2,3,4-tetrahydroisoquinoline hydrochloride; 7-Bromotetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-7-bromoisoquinoline hydrochloride; 7-Bromo-THIQ HCl; 7-Br-THIQ·HCl; 7-Bromo-1,2,3,4-tetrahydro-isoquinoline hydrochloride
EINECS	Contact for details

Quality Control

Our 7-Bromo-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent quality suitable for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.